Just put these on the Les Paul a few days ago, and am extremely amazed with them. They've got a much clearer bottom end "attack" than any nickel alloys I've tried, and have enabled me to get a classic Led Zeppelin sound that had been eluding me. Songs with lots of bottom end (Whole Lotta Love, Kashmir, Dazed & Confused, etc.) really sound great with these. The opening instrumental section of Rush's "2112" also sounds awesome with them. If you like low end crunch without a muddy tone, these things are fantastic. The only down-side are that they're a bit rougher than some others I've tried, but good calluses solve that.