"Loco" has several different meanings:
*In Vodou, Loco (also Loko, Loko Atisou) is a Rada nation loa, patron of healers and plants, especially trees. His is married to Ayizan.
*"Loco" is the first, and probably best known, single by the now-defunct band Coal Chamber
* Loco is also an abbreviation for locomotive.
*''Loco'', from Spanish, is slang for insane or crazy
*''Loco'', is the South American name of Abalone
*Loco, in musical software, is an audio programming language designed to be for sound what Logo is for graphics.
*"Loco" and ''Loco'', a 2001 song and album by the Fun Lovin' Criminals.
*Loco is a distribution of GNU/Linux.
*Loco, Oklahoma is a place in Stephens County; the zip code is 73442.
*Manuel Antonio Cange, a footballer known more commonly as 'Loco'