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Louis Knox Barlow (born July 17, 1966) is an American alternative rock musician and songwriter. A founding member of the groups Dinosaur Jr., Sebadoh and The Folk Implosion, Barlow is credited with helping to pioneer the lo-fi style of rock music in the late 1980s and early 1990s. His first band, which was formed in Amherst, Massachusetts, was Deep Wound.

Barlow has released four solo albums.